Author

M. Foster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:differential expression· 3 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

D. Potter· 2 shared K. Stachowski· 2 shared V. Wysocki· 2 shared A. Gruszczynska· 1 shared A. Heard· 1 shared A. Norris· 1 shared A. Unnikrishnan· 1 shared A. Y. Kim· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

D. Potter

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Solution structure, dynamics and tetrahedral assembly of Anti-TRAP, a homo-trimeric triskelion-shaped regulator of tryptophan biosynthesis in Bacillus subtilis

C. A. McElroy, E. C. Ihms, D. Kumar Yadav, M. Holmquist, V. Wadhwa, V. Wysocki, P. Gollnick, M. Foster

This study determines the solution structure and dynamics of Anti-TRAP, revealing its trimeric and dodecameric forms and their roles in TRAP inhibition.

bioRxiv · Jun 29, 2023 · PreprintBiochemistry

Costimulatory domains direct distinct fates of CAR-driven T cell dysfunction

M. E. Selli, J. H. Landmann, M. Terekhova, J. Lattin, A. Heard, Y.-S. Hsu, T.-C. Chang, J. M. Warrington, H. Ha, N. Kingston, G. Hogg, M. Slade, M. M. Berrien-Elliot, M. Foster, S. Kersting-Schadek, , N. Singh

This study identifies that chronic activation of 41BB-based CARs leads to a novel T cell dysfunction state, distinct from exhaustion, which can be mitigated by disrupting FOXO3.

bioRxiv · Jan 26, 2023 · PreprintImmunology

A collaborative approach to improving representation in viral genomic surveillance

P. Kim, A. Y. Kim, J. J. Newman, E. Cella, T. C. Bishop, P. J. Huwe, O. N. Uchakina, R. J. McKallip, V. L. Mack, M. P. Hill, I. V. Ogungbe, O. Adeyinka, S. Jones, G. Ware, J. L. Carroll, , J. P. Kamil

This paper develops a collaborative genomic surveillance model to improve representation in rural and minority communities, generating over 1,000 SARS-CoV-2 genomes and identifying new variants.

bioRxiv · Oct 19, 2022 · PreprintMicrobiology

Uncovering Xenobiotics in the Dark Metabolome using Ion Mobility Spectrometry, Mass Defect Analysis and Machine Learning

M. Foster, M. Rainey, C. Watson, J. N. Dodds, F. Fernandez, E. Baker

The paper develops a workflow combining ion mobility spectrometry, mass defect analysis, and machine learning to identify xenobiotics in metabolomic data, successfully annotating PFAS in human serum.

bioRxiv · Nov 21, 2021 · PreprintBiochemistry

Unloxing the assembly and activation mechanism of Cre recombinase using Cryo-EM

K. Stachowski, A. Norris, D. Potter, V. Wysocki, M. Foster

This paper determines cryo-EM structures of Cre-loxP assembly intermediates to elucidate mechanisms of site selection, strand cleavage order, and activation in the Cre recombinase system.

bioRxiv · Jul 31, 2021Biochemistry

DNA Binding Induces a cis to trans Switch in Cre Recombinase to Enable Intasome Assembly

A. Unnikrishnan, C. D. Amero, D. K. Yadav, K. Stachowski, D. Potter, M. Foster

This paper uses NMR to show that Cre recombinase undergoes a cis-to-trans conformational switch upon DNA binding, enabling intasome assembly and DNA recombination.

bioRxiv · May 24, 2020Biophysics