The nucleocytosolic O-fucosyltransferase Spindly affects protein expression and virulence in Toxoplasma gondii
G. Bandini, C. Agop-Nersesian, H. van der Wel, M. Mandalasi, H. Kim, C. M. West, J. Samuelson
This paper identifies TgSPY as the O-fucosyltransferase in Toxoplasma gondii, showing it modifies proteins but is not essential for growth, yet affects protein levels and virulence in mice.
bioRxiv · Aug 30, 2020Microbiology