C. M. West

This paper identifies TgFBXL2, an F-box protein in Toxoplasma gondii, which represses feline-restricted genes required for sexual commitment by modulating SCF-E3 ubiquitin ligase activity.

This study shows that TgPHYa, an oxygen-sensing protein in Toxoplasma, is essential for parasite virulence and survival in immune cells by enabling tryptophan scavenging during IFN-gamma-induced nutritional immunity.

This paper identifies TgSPY as the O-fucosyltransferase in Toxoplasma gondii, showing it modifies proteins but is not essential for growth, yet affects protein levels and virulence in mice.

This study identifies Gat1, a glycogenin homolog, as essential for adding the terminal sugar to Skp1 in Toxoplasma gondii, which is critical for parasite growth.

This paper investigates how Skp1 dimerization hides its F-box protein binding site, showing that a mutation disrupts dimerization and allows Skp1 to bind F-box proteins.

The paper investigates the relationship between HIF1a and androgen signaling pathways in prostate cancer, finding they operate independently and identify shared genes associated with poor prognosis.

This paper identifies TgFBXO1 as an F-box protein essential for daughter cell scaffold function in Toxoplasma gondii, demonstrating its role in parasite replication.