Author

C. Alleva

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 3 Organism:human· 2 Approach:statistical model· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1

Frequent Co-Authors

D. Drew· 2 shared D. Mitrovic· 2 shared L. Delemotte· 2 shared M. Bonaccorsi· 2 shared C. Fahlke· 1 shared M. Alfonso-Prieto· 1 shared N. Dmitrieva· 1 shared P. Carloni· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

D. Drew

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Author profile →

3 papers

Recent·Most cited

Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters

N. Dmitrieva, S. Gholami, C. Alleva, P. Carloni, M. Alfonso-Prieto, C. Fahlke

This study elucidates the transport mechanism of DgoT, a bacterial homolog of SLC17 transporters, revealing key proton and substrate interactions that drive conformational changes and transport.

bioRxiv · Feb 7, 2024Biophysics

Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning

D. Mitrovic, S. E. McComas, C. Alleva, M. Bonaccorsi, D. Drew, L. Delemotte

The paper uses coevolution analysis and comparative modeling to predict the transport cycle states of the sugar porter superfamily and defines molecular determinants of the cycle.

bioRxiv · Sep 24, 2022Biophysics

Determinants of sugar-induced influx in the mammalian fructose transporter GLUT5

S. McComas, T. Reichenbach, D. Mitrovic, C. Alleva, M. Bonaccorsi, L. Delemotte, D. Drew

This study shows GLUT5 transitions through an occluded state similar to PfHT1, with fructose binding lowering energetic barriers and enabling fast sugar flux through allosteric coupling.

bioRxiv · Jun 17, 2022Biophysics