Author

S. McComas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Organism:human· 1

Frequent Co-Authors

L. Delemotte· 2 shared C. Alleva· 1 shared D. Drew· 1 shared D. Mitrovic· 1 shared K. Choudhury· 1 shared M. Bonaccorsi· 1 shared M. Kasimova· 1 shared R. J. Howard· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

L. Delemotte

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2 papers

Recent·Most cited

Determinants of sugar-induced influx in the mammalian fructose transporter GLUT5

S. McComas, T. Reichenbach, D. Mitrovic, C. Alleva, M. Bonaccorsi, L. Delemotte, D. Drew

This study shows GLUT5 transitions through an occluded state similar to PfHT1, with fructose binding lowering energetic barriers and enabling fast sugar flux through allosteric coupling.

bioRxiv · Jun 17, 2022Biophysics

An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing Asparagine

K. Choudhury, M. Kasimova, S. McComas, R. J. Howard, L. Delemotte

This paper uses molecular modeling and simulations to propose a stable open state model for the NavMs channel, featuring a π-helix and conserved asparagine residue, resolving disputes about its functional annotation.

bioRxiv · Jul 28, 2021Biophysics