Author

C. Blau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Research Focus:protein structure prediction· 3 Approach:deep learning· 2 Organism:bacteria (other)· 1 Approach:Bayesian inference· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Lindahl· 3 shared L. Yvonnesdotter· 2 shared R. J. Howard· 2 shared U. Rovsnik· 2 shared B. O. Forsberg· 1 shared L. Axelsson· 1 shared M. Carroni· 1 shared M. Lycksell· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiophysics

E. Lindahl

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3 papers

Recent·Most cited

Automated simulation-based membrane-protein refinement into cryo-EM data

L. Yvonnesdotter, U. Rovsnik, C. Blau, M. Lycksell, R. J. Howard, E. Lindahl

This paper introduces an automated method using density-guided molecular dynamics simulations to refine membrane-protein models into cryo-EM maps, showing improved model quality and pixel-size correction.

bioRxiv · Oct 28, 2022Biophysics

Gentle and fast all-atom model refinement to cryo-EM densities via Bayes' approach

C. Blau, L. Yvonnesdotter, E. Lindahl

The paper introduces a Bayesian refinement method for cryo-EM density maps, improving structure modeling by balancing fit and stereochemistry with a new potential and adaptive force scaling.

bioRxiv · Sep 30, 2022 · PreprintBiophysics

Characterization of the dynamic resting state of a pentameric ligand-gated ion channel by cryo-electron microscopy and simulations

U. Rovsnik, Y. Zhuang, L. Axelsson, B. O. Forsberg, V. T. Lim, M. Carroni, C. Blau, R. J. Howard, E. Lindahl

The paper uses cryo-EM and simulations to characterize the resting and activating states of GLIC, revealing structural changes and energy landscape dynamics.

bioRxiv · Jun 19, 2020 · PreprintBiophysics