In Vivo Transcriptomic Profiling using Cell Encapsulation Identifies Effector Pathways of Systemic Aging
O. Mashinchian, X. Hong, J. Michaud, E. Migliavacca, G. Lefebvre, C. Boss, F. De Franceschi, E. Le Moal, J. Collerette-Tremblay, J. Isern, S. Metairon, F. Raymond, P. Descombes, N. Bouche, P. Munoz-Canoves, , C. F. Bentzinger
This study uses cell encapsulation to profile systemic aging in vivo and identifies Myc and E2F activation, senescence, and suppressed myogenic differentiation as key pathways.
bioRxiv · Mar 9, 2020Bioengineering