Author

J. Isern

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

P. Munoz-Canoves· 2 shared A. Schambach· 1 shared B. Qin· 1 shared B. Wang· 1 shared C. Boss· 1 shared C. F. Bentzinger· 1 shared C. J. Mann· 1 shared C. Liu· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

P. Munoz-Canoves

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Author profile →

3 papers

Recent·Most cited

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

L. Han, X. Wei, C. Liu, G. Volpe, Z. Zhuang, X. Zou, Z. Wang, T. Pan, Y. Yuan, X. Zhang, P. Fan, P. Guo, Y. Lai, Y. Lei, X. Liu, , Z. Liu

The paper presents a single-cell transcriptomic atlas of Macaca fascicularis, identifying cell interactions and disease associations.

Nature · Apr 13, 2022Peer-reviewedCell Biology

mRNA translation control by Dhx36 binding to 5' UTR G-quadruplex structures is essential for skeletal muscle stem cell regenerative functions

X. Chen, J. Yuan, G. Xue, S. Campanario Sanz, D. Wang, W. Wang, X. Mou, M. I. I. Umar, J. Isern, Y. Zhao, L. He, Y. Li, C. J. Mann, X. Yu, L. Wang, , H. Wang

This study identifies Dhx36 as essential for skeletal muscle stem cell regeneration by regulating mRNA translation through binding and unwinding 5' UTR G-quadruplex structures.

bioRxiv · Aug 30, 2020Cell Biology

In Vivo Transcriptomic Profiling using Cell Encapsulation Identifies Effector Pathways of Systemic Aging

O. Mashinchian, X. Hong, J. Michaud, E. Migliavacca, G. Lefebvre, C. Boss, F. De Franceschi, E. Le Moal, J. Collerette-Tremblay, J. Isern, S. Metairon, F. Raymond, P. Descombes, N. Bouche, P. Munoz-Canoves, , C. F. Bentzinger

This study uses cell encapsulation to profile systemic aging in vivo and identifies Myc and E2F activation, senescence, and suppressed myogenic differentiation as key pathways.

bioRxiv · Mar 9, 2020Bioengineering