3D light sheet fluorescence microscopy of lungs to dissect local host immune - Aspergillus fumigatus interactions
J. Amich, Z. Mokhtari, M. Strobel, E. Vialetto, N. Kalleda, K. Jarick, C. Brede, A.-L. Jordan-Garrote, S. Thusek, K. Schmiedgen, B. Arslan, J. Pinnecker, C. R. Thornton, M. Gunzer, S. Krappmann, , A. Beilhack
This paper uses 3D light sheet fluorescence microscopy to analyze fungal growth and immune responses in murine models of invasive pulmonary aspergillosis, revealing differences in fungal architecture and immune cell interactions across immunosuppressive regimens.
bioRxiv · Jun 5, 2019Immunology