Author

M. Gunzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 6 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 7 Organism:mouse· 6 Assay:imaging· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Sickmann· 2 shared A. A. Tuz· 1 shared A. B. Malik· 1 shared A. Beer· 1 shared A. Beilhack· 1 shared A. Gkasti· 1 shared A. Grueneboom· 1 shared A. Hasenberg· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Sickmann

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

NEUTROPHILS ARE INDISPENSABLE FOR ADVERSE CARDIAC REMODELING IN HEART FAILURE

S. V. Antipenko, N. Mayfield, M. Jinno, M. Gunzer, M. A. Ismahil, T. Hamid, S. S. Prabhu, G. Rokosh

This study shows neutrophils drive adverse cardiac remodeling in heart failure by promoting fibrosis and LV dysfunction through NETosis and systemic activation.

bioRxiv · Oct 31, 2023Immunology

Peyers Patch B cells undergo cell death via neutrophil-released toxic DNA following sterile tissue injury

A. A. Tuz, A. Beer, M. Gallert, D. Ttoouli, S. Ghosh, S. P. Sata, A. Kraus, F. Zwirnlein, V. Kaygusuz, V. Lakovic, A. Qefalia, M. Antler, S. Korste, B. Kaltwasser, H. Abdelrahman, , V. Singh

The paper shows that sterile tissue injury causes B cell death in Peyers patches via neutrophil-released toxic DNA, leading to tissue shrinkage and reduced secretory IgA.

bioRxiv · Nov 9, 2022Immunology

Computer-Vision Stabilized Intravital Imaging Reveals Lung Capillary Neutrophil Dynamics Crucial for Lung Host-Defense Function

Y. Tsukasaki, K. Bachmaier, J. C. Joshi, B. Joshi, P. T. Toth, Z. Hong, S. Nepal, M. Gunzer, J. Cho, D. Mehta, C. Tiruppathi, S. Pinho, J. Rehman, A. B. Malik

This study uses CASTii to analyze lung capillary neutrophil dynamics, revealing their role in host defense and response to infection.

bioRxiv · Apr 19, 2021 · PreprintMicrobiology

Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 variants of concern by HMOX-1 upregulation in human cells

V. T. K. Le-Trilling, D. Mennerich, C. Schuler, R. Sakson, J. K. Lill, D. Kopczynski, S. Loroch, Y. Flores-Martinez, B. Katschinski, K. Wohlgemuth, M. Gunzer, F. Meyer, U. Dittmer, A. Sickmann, M. Trilling

bioRxiv · Nov 18, 2020Microbiology

Microbial activation converts neutrophils into anti-tumor effectors

A. O. Yam, J. Bailey, F. Lin, A. Jakovija, C. Counoupas, J. A. Triccas, M. Gunzer, T. Bald, S. T. Grey, T. Chtanova

This study shows microbial bioparticles convert neutrophils into anti-tumor effectors by altering their phenotype and function, leading to tumor growth inhibition.

bioRxiv · Aug 21, 2020 · PreprintImmunology

3D light sheet fluorescence microscopy of lungs to dissect local host immune - Aspergillus fumigatus interactions

J. Amich, Z. Mokhtari, M. Strobel, E. Vialetto, N. Kalleda, K. Jarick, C. Brede, A.-L. Jordan-Garrote, S. Thusek, K. Schmiedgen, B. Arslan, J. Pinnecker, C. R. Thornton, M. Gunzer, S. Krappmann, , A. Beilhack

This paper uses 3D light sheet fluorescence microscopy to analyze fungal growth and immune responses in murine models of invasive pulmonary aspergillosis, revealing differences in fungal architecture and immune cell interactions across immunosuppressive regimens.

bioRxiv · Jun 5, 2019Immunology

Efficient and specific Ly6G+ cell depletion: A change in the current practices toward more relevant functional analyses of neutrophils

J. Faget, G. Boivin, P.-B. Ancey, A. Gkasti, J. Mussard, C. Engblom, C. Pfirschke, J. Vazquez, N. Bendriss-Vermare, C. Caux, M.-C. Vozenin, M. J. Pittet, M. Gunzer, E. Meylan

The paper compares anti-Gr1 and anti-Ly6G antibodies for neutrophil depletion, showing anti-Ly6G's inefficacy in C57BL/6 mice but its potential for specific depletion when combined with a secondary antibody.

bioRxiv · Dec 18, 2018 · PreprintImmunology

Differential attenuation of β2 integrin-dependent and -independent neutrophil migration by Ly6G ligation

P. Cunin, P. Lee, E. Kim, A. Schmider, N. Cloutier, A. Pare, M. Gunzer, R. Soberman, S. Lacroix, E. Boilard, C. Lefort, P. Nigrovic

This study shows that Ly6G ligation selectively inhibits β2 integrin-dependent neutrophil migration in specific inflammatory contexts.

bioRxiv · Nov 1, 2018Immunology