Author

C. Brugger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Deaconescu· 2 shared J. Schwartz· 2 shared A. M. Deaconescu· 1 shared J. Son· 1 shared M. Filipovski· 1 shared S. Srirangam· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

A. Deaconescu

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3 papers

Recent·Most cited

IraM Remodels the RssB Segmented Helical Linker to Stabilize σs against Degradation by ClpXP

C. Brugger, S. Srirangam, A. Deaconescu

This paper reports the structural analysis of IraM bound to RssB, showing how IraM stabilizes σs against degradation by modulating RssB's conformation.

bioRxiv · Jan 7, 2023 · PreprintBiophysics

Structure of Phosphorylated-like ClpXP Adaptor RssB Reveals an Interface Switch for Activation

C. Brugger, J. Schwartz, M. Filipovski, A. M. Deaconescu

The paper presents the crystal structure of phosphorylated-like RssB adaptor bound to ClpXP, revealing conformational changes that enable activation through domain rearrangement.

bioRxiv · Dec 15, 2022 · PreprintBiophysics

Phospho-dependent Signaling during the General Stress Response by the Atypical Response Regulator and ClpXP Adaptor RssB

J. Schwartz, J. Son, C. Brugger, A. Deaconescu

This study reports crystal structures of RssB's receiver domain in unphosphorylated and phosphomimic forms, revealing structural differences and suggesting a novel signaling mechanism in E. coli's stress response.

bioRxiv · Jan 11, 2021Biophysics