BiochemistrybioRxiv
Structural insights into the complex of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator
M. Tariq, T. Ikeya, N. Togashi…·K. Tanaka
This study investigates the structural interaction between oncogenic KRas4BG12V and Rgl2RA, revealing a unique tetrameric complex formation that explains its hyperactivation of the RalA/B pathway.
DOI 10.26508/lsa.202302080