Author

C. C. King

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1

Frequent Co-Authors

B. R. Myers· 1 shared C. D. Arveseth· 1 shared C. Olivieri· 1 shared D. Bertinetti· 1 shared D. S. Hedeen· 1 shared F. W. Herberg· 1 shared G. Veglia· 1 shared I. B. Nelson· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

B. R. Myers

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1 paper

Recent·Most cited

A PKA Inhibitor Motif within Smoothened Controls Hedgehog Signal Transduction

J. T. Happ, C. D. Arveseth, J. Bruystens, D. Bertinetti, I. B. Nelson, C. Olivieri, D. S. Hedeen, J.-F. Zhu, J. L. Capener, J. W. Bröckel, L. Vu, C. C. King, V. L. Ruiz-Perez, G. Veglia, F. W. Herberg, , B. R. Myers

This study identifies a PKA inhibitor motif in Smoothened that blocks PKA activity, enabling GLI activation in the Hedgehog pathway, revealing a mechanism similar to the Wnt cascade.

bioRxiv · Jul 5, 2021Biochemistry