Author

L. Vu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Microbiology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:structural biology· 2

Frequent Co-Authors

C. D. James· 2 shared C. Yang· 2 shared D. Pyeon· 2 shared I. M. Morgan· 2 shared M. I. Khalil· 2 shared S. Chadha· 2 shared S. S. Taylor· 2 shared A. Ghosh· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. D. James

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer

M. I. Khalil, C. Yang, L. Vu, S. Chadha, H. Nabors, C. D. James, I. M. Morgan, D. Pyeon

This paper shows that MARCHF8 stabilizes HPV E7 by degrading CUL1 and UBE2L3, preventing E7 degradation in HPV+ HNC cells.

bioRxiv · Nov 3, 2023Microbiology

HPV E6 upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer

M. I. Khalil, C. Yang, L. Vu, S. Chadha, C. Welbon, C. D. James, I. M. Morgan, W. C. Spanos, D. Pyeon

bioRxiv · Sep 7, 2022Microbiology

Molecular-Dynamics Simulation Methods for Macromolecular Crystallography

D. C. Wych, P. C. Aoto, L. Vu, A. M. Wolff, D. L. Mobley, J. S. Fraser, S. S. Taylor, M. E. Wall

The paper applies molecular-dynamics simulations to macromolecular crystallography to refine protein structures and improve interpretation of electron density.

bioRxiv · Apr 4, 2022Biophysics

A PKA Inhibitor Motif within Smoothened Controls Hedgehog Signal Transduction

J. T. Happ, C. D. Arveseth, J. Bruystens, D. Bertinetti, I. B. Nelson, C. Olivieri, D. S. Hedeen, J.-F. Zhu, J. L. Capener, J. W. Bröckel, L. Vu, C. C. King, V. L. Ruiz-Perez, G. Veglia, F. W. Herberg, , B. R. Myers

This study identifies a PKA inhibitor motif in Smoothened that blocks PKA activity, enabling GLI activation in the Hedgehog pathway, revealing a mechanism similar to the Wnt cascade.

bioRxiv · Jul 5, 2021Biochemistry

Defining the Caprin-1 interactome in unstressed and stressed conditions

L. Vu, A. Ghosh, C. Tran, W. A. Tebung, H. Sidibé, K. Garcia-Mansfield, V. David-Dirgo, R. Sharma, P. Pirrotte, R. Bowser, C. Vande Velde

The paper identifies the Caprin-1 interactome under unstressed and stressed conditions, revealing novel components of stress granules and their association with ALS aggregates.

bioRxiv · Jan 6, 2021Cell Biology

The TPLATE subunit is essential for structural assembly of the endocytic TSET complex

K. Yperman, J. Wang, D. Eeckhout, J. Winkler, L. Vu, M. Vandorpe, P. Grones, E. Mylle, M. Kraus, R. Merceron, J. Nolf, E. Mor, P. De Bruyn, R. Loris, M. Potocky, , R. Pleskot

The paper determines the structural architecture of the plant TSET complex and identifies key interactions essential for its assembly and function in endocytosis.

bioRxiv · Aug 13, 2020 · PreprintCell Biology