Author

c. C. Lachaud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

B. R. Gauthier· 2 shared F. Martin· 2 shared N. Cobo-vuilleumier· 2 shared P. I. Lorenzo· 2 shared A. C. Vertegaal· 1 shared A. Campo-Caro· 1 shared A. Campos Caro· 1 shared A. Dorronsoro· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

B. R. Gauthier

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Author profile →

2 papers

Recent·Most cited

LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice

N. Cobo-vuilleumier, S. Rodriguez-Fernandez, L. Lopez-Noriega, P. I. Lorenzo, J. M. Franco, c. C. Lachaud, E. Martin-Vazquez, R. Araujo Legido, A. Dorronsoro, R. Lopez-Fernandez-Sobrino, b. Fernandez-santos, D. Salas-Lloret, N. van Overbeek, M. Ramos-Rodriguez, C. Mateo-Rodriguez, , B. R. Gauthier

This study shows that activating LRH-1/NR5A2 reduces inflammation in T1D by altering immune cell metabolism and improves human islet function in mice.

bioRxiv · Sep 18, 2023 · PreprintCell Biology

The Metabesity Factor HMG20A Potentiates Astrocyte Survival and Reactivity Preserving Neuronal Integrity

P. I. Lorenzo, E. Fuente-Martin, J. M. Mellado-Gil, J. A. Guerrero Martinez, N. Cobo-Vuilleumier, V. Comaills, E. Martin Vazquez, S. Y. Romero-Zerbo, J. Munoz Franco, J. A. Perez-Caballo, S. Rivero-Canalejo, A. Campo-Caro, C. C. Lachaud, M. Aguilar Diosdado, E. Garcia Fuentes, , B. R. Gauthier

This paper shows HMG20A promotes astrocyte survival and reactivity in the adult brain, preserving neuronal integrity under metabolic stress.

bioRxiv · Feb 15, 2021 · PreprintCell Biology