Ghrelin delays premature aging in Hutchinson-Gilford progeria syndrome
M. Ferreira-Marques, A. Carvalho, A. C. Franco, A. Leal, M. Botelho, S. Carmo-Silva, R. Aguas, L. Cortes, V. Lucas, A. C. Real, C. Lopez-Otin, X. Nissan, L. Pereira de Almeida, C. Cavadas, C. A. Aveleira
This study shows ghrelin improves cellular and organismal features of HGPS by promoting autophagy and clearing progerin, extending lifespan in a mouse model.
bioRxiv · May 2, 2023Physiology