A "torn bag mechanism" of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)
T. Visnovitz, D. Lenzinger, A. Koncz, P. M. Vizi, T. Barkai, K. V. Vukman, A. Galinsoga, K. Nemeth, K. Fletcher, Z. I. Komlosi, C. Cserep, A. Denes, P. Lorincz, G. Valcz, E. I. BUZAS
The paper identifies a 'torn bag mechanism' for small extracellular vesicle release through membrane rupture of amphisomes, showing that both ILVs and small EVs originate from different pathways.
bioRxiv · Jan 30, 2024 · PreprintCell Biology