Ehrlichia Wnt short linear motif ligand mimetic deactivates the Hippo pathway to engage the anti-apoptotic Yap-GLUT1-BCL-xL axis
C. D. Byerly, L. L. Patterson, N. Pittner…·J. W. McBride
This study shows Ehrlichia chaffeensis uses a Wnt-like SLiM to deactivate Hippo signaling, activating Yap and the anti-apoptotic Yap-GLUT1-BCL-xL axis, enhancing infection.