Experimental Evolution in vivo to Identify Selective Pressures During Pneumococcal Colonization
V. S. Cooper, E. Honsa, H. Rowe, C. Deitrick, A. R. Iverson, J. J. Whittall, S. L. Neville, C. A. McDevitt, C. Kietzman, J. W. Rosch
This study uses experimental evolution in mice to identify genetic adaptations of Streptococcus pneumoniae during nasal colonization and reveals fitness trade-offs in different host niches.
bioRxiv · Jan 15, 2020Microbiology