Predicting the Three-dimensional Structure of the c-KIT Oncogene Promoter and the Dynamics of Strongly Coupled Guanine-Quadruplexes
E. Bignon, A. Spinello, T. Miclot, L. D'Anna, C. Ducani, S. Grandemange, G. Barone, A. MONARI, A. Terenzi
The paper predicts the 3D structure of the c-KIT promoter's G4s and shows how their coupling affects structure formation and drug discovery potential.
bioRxiv · Feb 23, 2023 · PreprintBiophysics