Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing.
E. Marhuenda, C. Fabre, C. Zhang, M. Martin-Fernandez, T. Iskratsch, A. Saleh, L. Bauchet, J. Cambedouzou, J.-P. Hugnot, H. Duffau, J. Dennis, D. Cornu, N. Bakalara
This study shows that glioma stem cells exhibit optimal migration at specific matrix stiffness, mediated by MGAT5-dependent N-glycan branching.
bioRxiv · Sep 25, 2020Cell Biology