Author

J.-P. Hugnot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. Pineau· 2 shared H. Duffau· 2 shared A. Bouzid· 1 shared A. Darlix· 1 shared A. Saleh· 1 shared A.-L. Chaves Valadao· 1 shared C. Fabre· 1 shared C. Gongora· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

D. Pineau

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The crosstalk between DNA-PK and cGAS drives tumor immunogenicity

C. Taffoni, J. Marines, H. Chamma, M. Saccas, A. Bouzid, S. Guha, A.-L. Chaves Valadao, K. Polak, M. Del Rio, C. Gongora, D. Pineau, J.-P. Hugnot, K. Kissa, L. Fontenille, F. P. Blanchet, , N. Laguette

This study shows DNA-PK and cGAS work together to drive inflammation in tumors, affecting immunogenicity and patient outcomes.

bioRxiv · Jun 8, 2022 · PreprintCancer Biology

Identification of CRYAB+ KCNN3+ SOX9+ astro-like and EGFR+ PDGFRA+ OLIG1+ oligo-like tumoral cells in diffuse low-grade gliomas and implication of Notch1 signalling in their genesis

M. Augustus, D. Pineau, F. Aimond, S. Azar, D. Lecca, N. Leventoux, F. Scamps, S. Muxel, A. Darlix, W. Ritchie, C. Goze, V. Rigau, H. Duffau, J.-P. Hugnot

The paper identifies two distinct tumoral cell subtypes in IDH1-mutated low-grade gliomas and shows NOTCH1 signaling influences their characteristics.

bioRxiv · Feb 9, 2021Cancer Biology

Glioma stem cells invasive phenotype at optimal stiffness is driven by MGAT5 dependent mechanosensing.

E. Marhuenda, C. Fabre, C. Zhang, M. Martin-Fernandez, T. Iskratsch, A. Saleh, L. Bauchet, J. Cambedouzou, J.-P. Hugnot, H. Duffau, J. Dennis, D. Cornu, N. Bakalara

This study shows that glioma stem cells exhibit optimal migration at specific matrix stiffness, mediated by MGAT5-dependent N-glycan branching.

bioRxiv · Sep 25, 2020Cell Biology