Author

C. Fleck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Organism:Arabidopsis· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:E. coli· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. M. Keizer· 2 shared A. Schnittger· 1 shared E. Wijnker· 1 shared F. Büke· 1 shared F. Seifert· 1 shared J. Chalupsky· 1 shared J. N. A. Vink· 1 shared J. van Lopik· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

E. M. Keizer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single Cell Variability of CRISPR-Cas Interference and Adaptation

R. E. McKenzie, E. M. Keizer, J. N. A. Vink, J. van Lopik, F. Büke, V. Kalkman, C. Fleck, S. J. Tans, S. J. J. Brouns

The paper studies CRISPR-Cas interference and adaptation in E. coli, finding cell-to-cell variability in clearance times due to primed adaptation, with Cascade binding as the main source of heterogeneity.

bioRxiv · Jul 21, 2021Microbiology

Live cell imaging of meiosis in Arabidopsis thaliana - a landmark system

M. A. Prusicki, E. M. Keizer, R. P. van Rosmalen, S. Komaki, F. Seifert, K. Müller, E. Wijnker, C. Fleck, A. Schnittger

The paper establishes a live cell imaging system to study meiotic progression in Arabidopsis, identifying 11 recurrent states that serve as landmarks for analyzing meiosis dynamics and evaluating mutants.

bioRxiv · Oct 18, 2018Cell Biology

Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor

O. S. Yousefi, M. Guenther, M. Hoerner, J. Chalupsky, M. Wess, S. M. Brandl, R. W. Smith, C. Fleck, T. Kunkel, M. D. Zurbriggen, T. Hoefer, W. Weber, W. W. A. Schamel

The study shows that the half-life of the ligand-T cell receptor complex determines T cell activation, supporting the kinetic proofreading model.

bioRxiv · Oct 1, 2018Immunology