ImmunologybioRxiv
Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor
O. S. Yousefi, M. Guenther, M. Hoerner…·W. W. A. Schamel
The study shows that the half-life of the ligand-T cell receptor complex determines T cell activation, supporting the kinetic proofreading model.
DOI 10.7554/elife.42475