Author

C. Frorup

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. A. Sondergaard Svane· 2 shared J. Storling· 2 shared S. Kaur· 2 shared F. Pociot· 1 shared J. Mendes Lopes de Melo· 1 shared K. Henriksen· 1 shared R. Gerwig· 1 shared T. Floyel· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

C. A. Sondergaard Svane

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2 papers

Recent·Most cited

Beta-Cell Pyroptosis - A Burning Flame in Type 1 Diabetes?

C. Frorup, C. A. Sondergaard Svane, K. Henriksen, S. Kaur, J. Storling

This paper challenges the dogma that beta-cell death in T1D is primarily apoptotic by presenting evidence for pyroptosis as a key mechanism driving islet inflammation and beta-cell demise.

bioRxiv · Jan 5, 2024 · PreprintCell Biology

Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC- βH5 beta cells

C. Frorup, R. Gerwig, C. A. Sondergaard Svane, J. Mendes Lopes de Melo, T. Floyel, F. Pociot, S. Kaur, J. Storling

This study examines how pro-inflammatory cytokines affect EndoC-βH5 beta cells, showing increased apoptosis, mitochondrial dysfunction, and transcriptomic changes linked to type 1 diabetes.

bioRxiv · Nov 29, 2022 · PreprintCell Biology