Characterisation of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC- βH5 beta cells
C. Frorup, R. Gerwig, C. A. Sondergaard Svane, J. Mendes Lopes de Melo, T. Floyel, F. Pociot, S. Kaur, J. Storling
This study examines how pro-inflammatory cytokines affect EndoC-βH5 beta cells, showing increased apoptosis, mitochondrial dysfunction, and transcriptomic changes linked to type 1 diabetes.
bioRxiv · Nov 29, 2022 · PreprintCell Biology