Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma
C. Galvan, A. Flores, V. Cerillos, I. Avila, C. Murphy, W. Zheng, T. T. To, H. Christofk, W. Lowry
This study investigates metabolic flexibility in hair follicle stem cell-derived squamous cell carcinoma by blocking glycolysis and glutaminolysis, showing tumors can compensate by upregulating lactate consumption.
bioRxiv · Oct 16, 2023Cancer Biology