Escape of TLR5 Recognition by Leptospira spp: A Rationale for Atypical Endoflagella
M. Holzapfel, D. Bonhomme, J. Cagliero, F. Vernel-Pauillac, M. Fanton d'Andon, S. Bortolussi, L. Fiette, C. Goarant, E. Wunder, M. Picardeau, A. Ko, D. Werling, M. Matsui, I. Gomberts Boneca, C. Werts
This study investigates TLR5 recognition of Leptospira spp. and finds that their flagellins are highly stable and centrally located, allowing them to evade TLR5 detection.
bioRxiv · May 30, 2020Immunology