Cancer BiologybioRxiv
B-Cell Precursor Acute Lymphoblastic Leukemia elicits an Interferon-α/β response in Bone Marrow-derived Mesenchymal Stroma.
M. W. E. Smeets, E. M. P. Steeghs, J. Orsel…·M. L. den Boer
This study shows BCP-ALL cells induce an IFN-α/β gene signature in MSCs via tunneling nanotubes, but this does not enhance leukemic cell survival or drug resistance.
DOI 10.3324/haematol.2023.283494