Core-N-glycans are atypically abundant at the neuronal surface and regulate glutamate receptor signaling
C.-L. Zhang, C. Moutoussamy, M. Tuffery, A. Varangot, R. A. Piskorowski, C. Hanus
The paper shows core-N-glycans are abundant on neuronal surfaces and impair NMDA receptor-dependent synaptic plasticity by reducing synaptic AMPA receptor expression and slowing AMPA receptor desensitization.
bioRxiv · Mar 25, 2024 · PreprintCell Biology