Author

C. Harmon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:clinical cohort / trial· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. West· 2 shared K. Luddy· 2 shared M. Robertson-Tessi· 2 shared A. Ardaseva· 1 shared A. Bui· 1 shared A. R. A. Anderson· 1 shared D. F. K. Williamson· 1 shared D. K. Eggers· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

J. West

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3 papers

Recent·Most cited

Solvation Free Energy in Governing Equations for DNA Hybridization, Protein-Ligand Binding, and Protein Folding

C. Harmon, A. Bui, J. M. Espejo, M. Gancayco, J. M. Le, J. Rangel, D. K. Eggers

This paper examines the thermodynamics of biomolecular interactions using a governing equation that includes solvation free energy, showing its impact on DNA hybridization, protein-ligand binding, and protein folding.

bioRxiv · Mar 15, 2024Biochemistry

Evolutionary exploitation of PD-L1 expression in hormone receptor positive breast cancer

J. West, D. Park, C. Harmon, D. Williamson, P. Ashcroft, D. Maestrini, A. Ardaseva, R. Bravo, P. Sahoo, H. Khong, K. Luddy, M. Robertson-Tessi

The paper models how timing of aromatase inhibitor and immune checkpoint inhibitor therapies affects tumor burden and metastatic potential in hormone receptor positive breast cancer.

bioRxiv · Oct 26, 2018 · PreprintCancer Biology

The immune checkpoint kick start: Optimization of neoadjuvant combination therapy using game theory

J. West, M. Robertson-Tessi, K. Luddy, D. S. Park, D. F. K. Williamson, C. Harmon, H. T. Khong, J. Brown, A. R. A. Anderson

The paper develops a mathematical model to optimize neoadjuvant combination therapy for ER+ breast cancer by balancing tumor burden and metastatic potential using game theory.

bioRxiv · Jun 18, 2018Cancer Biology