Author

C. Hogan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. P. Morton· 2 shared M. Alatsatianos· 2 shared O. J. Sansom· 2 shared A. Offergeld· 1 shared A. Padilha· 1 shared A. Zaragkoulias· 1 shared B. Salvador· 1 shared B. Salvador-Barbero· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

J. P. Morton

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3 papers

Recent·Most cited

Oncogenic KRAS cells use Wnt signalling and cell dormancy to override homeostatic cell elimination mechanisms in adult pancreas.

B. Salvador-Barbero, M. Alatsatianos, J. P. Morton, O. J. Sansom, C. Hogan

This study shows that oncogenic KRAS cells in the adult pancreas evade elimination by using Wnt signaling and cell dormancy.

bioRxiv · Feb 13, 2024Cell Biology

Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids

E. Valle-Encinas, N. Aleksieva, C. Velasco Martinez, M. Dawes, M. Zverev, M. Muller, A. Offergeld, M. J. Smalley, C. Hogan, S. J. Forbes, T. G. Bird, T. C. Dale

This study investigates the role of canonical Wnt signaling in BEC-to-hepatocyte conversion during liver injury and shows its impact on epithelial cell plasticity in hepatic organoids.

bioRxiv · Nov 9, 2020 · PreprintCell Biology

KRASG12D mutant cells are outcompeted by wild type neighbours in adult pancreas in an EPHA2-dependent manner.

W. Hill, A. Zaragkoulias, B. Salvador, G. Parfitt, M. Alatsatianos, A. Padilha, S. Porazinski, T. E. Woolley, J. P. Morton, O. J. Sansom, C. Hogan

This study shows that KRASG12D mutant cells are outcompeted by wild-type cells in the adult pancreas, dependent on EphA2 signaling, leading to tissue clearance and reduced premalignant lesions.

bioRxiv · Aug 4, 2020Cell Biology