IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport
M. Anitei, F. Bruno, C. Valkova, E. Cirri, T. Dau, I. Mestres Lascano, F. Calegari, C. Kaether
The paper shows that IER3IP1 mutations cause microcephaly by blocking ER-Golgi transport, leading to neuronal migration defects and ER distension.
bioRxiv · Jan 17, 2024Cell Biology