Author

F. Bruno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Cascio· 1 shared A. Sala· 1 shared C. Colomba· 1 shared C. Federico· 1 shared C. Kaether· 1 shared C. Pina· 1 shared C. Sisu· 1 shared C. Valkova· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Cascio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport

M. Anitei, F. Bruno, C. Valkova, E. Cirri, T. Dau, I. Mestres Lascano, F. Calegari, C. Kaether

The paper shows that IER3IP1 mutations cause microcephaly by blocking ER-Golgi transport, leading to neuronal migration defects and ER distension.

bioRxiv · Jan 17, 2024Cell Biology

Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles

D. Ragusa, Y. Ciciro, C. Federico, S. Saccone, F. Bruno, R. Saeedi, C. Sisu, C. Pina, A. Sala, S. Tosi

This study creates a t(7;12) AML model in K562 cells that mirrors patient-specific gene expression and features, aiding in understanding disease mechanisms.

bioRxiv · Jun 14, 2022Cancer Biology

Antiparasitic effect of stilbene and terphenyl compounds against Trypanosoma cruzi parasites

F. Bruno, G. Castelli, F. Vitale, S. Catanzaro, V. V. Badaco, M. Roberti, C. Colomba, A. Cascio, M. Tolomeo

This paper evaluates stilbene and terphenyl compounds against Trypanosoma cruzi, identifying ST18 as the most potent with low toxicity and caspase-1 activation in infected macrophages.

bioRxiv · Feb 23, 2021Microbiology