Discovery of a non-canonical prototype long-chain monoacylglycerol lipase through a structure-based endogenous reaction intermediate complex
N. Pinotsis, A. Krüger, N. Tomas, S. D. Chatziefthymiou, C. Litz, S. A. Mortensen, M. Daffe, H. Marrakchi, G. Antranikian, M. Wilmanns
The paper identifies and characterizes a non-canonical long-chain monoacylglycerol lipase using a high-resolution structure of an enzyme-substrate complex.
bioRxiv · Apr 7, 2022Biochemistry