Probabilities of HIV-1 bNAb development in healthy and chronically infected individuals
C. Kreer, C. Lupo, M. S. Ercanoglu, L. Gieselmann, N. Spisak, J. Grossbach, M. Schlotz, P. Schommers, H. Gruell, L. Dold, A. Beyer, A. Nourmohammad, T. Mora, A. Walczak, F. Klein
The paper uses sequence analysis to predict the likelihood of HIV-1 broadly neutralizing antibody (bNAb) development in healthy and infected individuals, finding that chronic infection is not required for bNAb generation.
bioRxiv · Jul 11, 2022Immunology