Author

C. Monit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

B. H. Hahn· 1 shared C. Dickson· 1 shared C. Ruis· 1 shared D. Jacques· 1 shared F. Bibollet-Ruche· 1 shared G. J. Towers· 1 shared J. A. Breuer· 1 shared J. Bryant· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

B. H. Hahn

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2 papers

Recent·Most cited

Macrophage activation of cGAS and TRIM5 distinguish pandemic and non-pandemic HIV

L. Zuliani-Alvarez, M. Larsen, J. Rasaiyaah, C. Monit, S. O. Perry, R. Sumner, S. McAlpine-Scott, C. Dickson, K. M. Rifat Faysal, L. Hilditch, R. Miles, F. Bibollet-Ruche, B. H. Hahn, T. Bocking, N. Pinotsis, , G. J. Towers

The paper compares pandemic HIV-1(M) and non-pandemic HIV strains, finding that non-pandemic strains activate cGAS and TRIM5 in myeloid cells, leading to antiviral responses and poor replication.

bioRxiv · Jan 21, 2022 · PreprintImmunology

Preadaptation of pandemic GII.4 noroviruses in hidden virus reservoirs years before emergence

C. Ruis, L. Lindesmith, M. Mallory, P. D. Brewer-Jensen, J. Bryant, V. Costantini, C. Monit, J. Vinje, R. S. Baric, R. A. Goldstein, J. A. Breuer

This paper shows that GII.4 noroviruses preadapt and circulate undetected for years before causing a new pandemic, with changes in host immunity enabling spread rather than genetic changes alone.

bioRxiv · Jun 3, 2019Evolutionary Biology