Author

D. Jacques

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Hadefi· 1 shared A. Lefort· 1 shared B. H. Hahn· 1 shared C. Dickson· 1 shared C. Liefferinckx· 1 shared C. Monit· 1 shared C. Moreno· 1 shared D. Lau· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. Hadefi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit altered digestive homeostasis

A. Hadefi, M. Leprovots, G. Dinsart, M. Marefati, M. Vermeersch, D. Monteyne, D. Perez-Morga, A. Lefort, F. Libert, L. Verset, C. Liefferinckx, C. Moreno, D. Jacques, E. Trepo, M.-I. Garcia

This study examines duodenal organoids from MASH patients and finds altered digestive homeostasis and junctional protein misexpression without barrier dysfunction.

bioRxiv · Jul 2, 2024 · PreprintCell Biology

Macrophage activation of cGAS and TRIM5 distinguish pandemic and non-pandemic HIV

L. Zuliani-Alvarez, M. Larsen, J. Rasaiyaah, C. Monit, S. O. Perry, R. Sumner, S. McAlpine-Scott, C. Dickson, K. M. Rifat Faysal, L. Hilditch, R. Miles, F. Bibollet-Ruche, B. H. Hahn, T. Bocking, N. Pinotsis, , G. J. Towers

The paper compares pandemic HIV-1(M) and non-pandemic HIV strains, finding that non-pandemic strains activate cGAS and TRIM5 in myeloid cells, leading to antiviral responses and poor replication.

bioRxiv · Jan 21, 2022 · PreprintImmunology

Fluorescence biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes

D. Lau, J. Walsh, W. Peng, V. Shah, S. Turville, D. Jacques, T. Böcking

This paper develops a fluorescence biosensor to quantify host protein interactions with HIV-1 capsid tubes in real-time using total internal reflection fluorescence microscopy.

bioRxiv · May 17, 2019Biophysics