BiophysicsbioRxiv
Liquid-liquid phase separation and aggregation of the prion protein globular domain modulated by a high-affinity DNA aptamer
C. O. Matos, Y. M. Passos, M. J. Amaral…·Y. Cordeiro
This study identifies DNA aptamers that modulate liquid-liquid phase separation of prion protein, revealing structural effects on aggregation and potential implications for TSEs.
DOI 10.1096/fj.201901897r