Author

Y. Cordeiro

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. d. S. Pinheiro· 1 shared A. R. Passos· 1 shared A. S. Pinheiro· 1 shared B. Macedo· 1 shared C. O. Matos· 1 shared G. Weber· 1 shared J. L. Silva· 1 shared M. d. S. Almeida· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. d. S. Pinheiro

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2 papers

Recent·Most cited

Copper drives prion protein phase separation and modulates aggregation

M. J. Do Amaral, A. R. Passos, S. Mohapatra, T. S. L. Da Silva, R. S. Carvalho, M. d. S. Almeida, A. d. S. Pinheiro, S. Wegmann, Y. Cordeiro

This study shows copper promotes prion protein condensation and aggregation through oxidative stress and co-partitioning, suggesting a dual role in copper buffering and toxicity.

Science Advances · Nov 3, 2023Peer-reviewedBiophysics

Liquid-liquid phase separation and aggregation of the prion protein globular domain modulated by a high-affinity DNA aptamer

C. O. Matos, Y. M. Passos, M. J. Amaral, B. Macedo, M. Tempone, O. C. L. Bezerra, M. O. Moraes, M. S. Almeida, G. Weber, S. Missailidis, J. L. Silva, A. S. Pinheiro, Y. Cordeiro

This study identifies DNA aptamers that modulate liquid-liquid phase separation of prion protein, revealing structural effects on aggregation and potential implications for TSEs.

bioRxiv · Jun 3, 2019Biophysics