ImmunologybioRxiv
RNA sensing via LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency
J. E. Stok, T. Oosenbrug, L. R. ter Haar…·A. G. van der Veen
This study shows that LGP2 is essential for type I IFN induction in ADAR1-deficient cells, with implications for AGS and cancer therapy.
DOI 10.15252/embj.2021109760