Author

C. Paulos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. A. Aksoy· 2 shared J. Hammerbacher· 2 shared A. Smith· 1 shared C. Herting· 1 shared C. Mart· 1 shared C. Timmers· 1 shared E. Czech· 1 shared E. Gottschalk· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

B. A. Aksoy

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clinically relevant orthotopic pancreatic cancer models for adoptive T cell therapy

N. K. Horvat, I. Karpovsky, M. Wyatt, M. A. Hall, M. Phillips, C. Herting, J. Hammons, Z. Mahdi, R. A. Moffitt, C. Paulos, G. B. Lesinski

This study compares two orthotopic PDAC mouse models to evaluate their suitability for studying adoptive T cell therapy, finding that the MT-5 model better replicates the stromal features of human PDAC.

bioRxiv · Sep 7, 2023 · PreprintCancer Biology

Discovering tumor-reactive T-cell receptors through single-cell sequencing of tumor-infiltrating lymphocytes

E. Gottschalk, B. A. Aksoy, P. Aksoy, M. Swiderska-Syn, C. Mart, L. Macpherson, M. Romeo, A. Smith, H. Knochelmann, C. Paulos, C. Timmers, J. Wrangle, M. P. Rubinstein, J. Hammerbacher

The paper uses single-cell sequencing of tumor-infiltrating lymphocytes to identify and validate novel tumor-reactive T-cell receptors in a mouse model.

bioRxiv · Nov 30, 2021 · PreprintImmunology

Computational and experimental optimization of T cell activation

B. A. Aksoy, E. Czech, C. Paulos, J. Hammerbacher

The paper optimizes T cell activation by identifying key culture factors and uncovering artifacts in bead-based activation methods.

bioRxiv · May 7, 2019 · PreprintImmunology