The spatial structure of the tumor immune microenvironment can explain and predict patient response in high-grade serous carcinoma
L. B. Van Kleunen, M. Ahmadian, M. D. Post, R. J. Wolsky, C. Rickert, K. Jordan, J. Hu, J. K. Richer, N. A. Marjon, K. Behbakht, M. J. Sikora, B. G. Bitler, A. Clauset
The paper uses spatial data from ovarian cancer tumors to show that spatial organization of the immune microenvironment correlates with patient outcomes and can predict treatment response.
bioRxiv · Jan 26, 2024Cancer Biology