C. H. Peters

This study identifies how LRMP inhibits cAMP-induced potentiation of HCN4 channels by disrupting intramolecular signaling, revealing isoform-specific interaction domains.

This study identifies the role of the funny current If in mediating the fight-or-flight response in cardiac pacemaker cells using machine learning and dynamic clamp experiments.

This study quantifies the funny current (If) in murine sinoatrial node myocytes, showing its persistent activity and dual role in driving membrane potential oscillations during pacemaking.

This paper identifies two ER proteins, LRMP and IRAG, that modulate HCN4 channel function differently, with LRMP inhibiting and IRAG enhancing HCN4 activity in a cAMP-independent manner.

This paper shows that the P1158S mutation in Nav1.4 makes skeletal muscle sodium channels sensitive to pH changes, leading to myotonia and periodic paralysis under acidic conditions.