ImmunologybioRxiv
T Cell Deficiency Precipitates Antibody Evasion and Emergence of Neurovirulent Polyomavirus
M. D. Lauver, K. N. Ayers, S. N. Carey…·A. E. Lukacher
The paper shows that T cell deficiency allows JCPyV to develop antibody-escape mutations, leading to neurovirulent variants.
DOI 10.7554/elife.83030