Microfluidic system-based time-course tracking of physical proximity between cells and its effect on gene expression for elucidating live single cancer-immune cell interactions
B. C. T. Flores, S. Chawla, N. Ma, C. Sanada, P. K. Kujur, L. T. D. Chinen, K. Hukari, M. Lynch, N. Ramalingam, D. Sengupta, S. S. Jeffrey
This study tracks physical proximity between NK and TNBC cells over time using a microfluidic system and links it to gene expression changes, revealing transcriptional memory in immune-cancer interactions.
bioRxiv · Nov 13, 2021 · PreprintCancer Biology