Single-Cell Analysis of 5-ALA Intraoperative Labeling Specificity for Glioblastoma
Z. Liu, A. Mela, J. Furnari, M. G. Argenziano, C. Kotidis, C. Sperring, N. Humala, J. N. Bruce, P. Canoll, P. A. Sims
This study shows 5-ALA labeling is not specific to transformed glioma cells but can label untransformed cells directly or via PpIX from surrounding tumor cells.
bioRxiv · Dec 17, 2022 · PreprintCancer Biology