Author

A. Mela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Mahajan· 2 shared N. Humala· 2 shared P. Canoll· 2 shared A. B. Heimberger· 1 shared A. M. Sonabend· 1 shared A. Quinones-Hinojosa· 1 shared B. Laffleur· 1 shared C. Dmello· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

A. Mahajan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

EZH2 inhibition sensitizes IDH1R132H mutant gliomas to histone deacetylase inhibitor.

L. Sprinzen, F. G. Garcia, A. Mela, L. Lei, P. Upadhyayula, A. Mahajan, N. Humala, L. Manier, R. M. Caprioli, A. Quinones-Hinojosa, P. Casaccia, P. Canoll

This study shows that EZH2 inhibition synergizes with HDAC inhibitors to kill IDH1R132H mutant glioma cells by reducing H3K27me3 and increasing H3K27ac.

bioRxiv · Jul 31, 2023Cancer Biology

Single-Cell Analysis of 5-ALA Intraoperative Labeling Specificity for Glioblastoma

Z. Liu, A. Mela, J. Furnari, M. G. Argenziano, C. Kotidis, C. Sperring, N. Humala, J. N. Bruce, P. Canoll, P. A. Sims

This study shows 5-ALA labeling is not specific to transformed glioma cells but can label untransformed cells directly or via PpIX from surrounding tumor cells.

bioRxiv · Dec 17, 2022 · PreprintCancer Biology

Septins coordinate cell wall integrity and lipid metabolism in a sphingolipid-dependent process

A. Mela, M. Momany

This study shows that septins in Aspergillus nidulans coordinate cell wall integrity and lipid metabolism through sphingolipid-dependent mechanisms, with distinct roles for core and noncore septins.

bioRxiv · Feb 9, 2020Cell Biology

CD8+ T-cell-mediated immunoediting influences genomic evolution and immune evasion in murine gliomas

J. R. Kane, J. Zhao, T. Tsujiuchi, B. Laffleur, A. Mahajan, G. Rao, A. Mela, C. Dmello, V. A. Arrieta, L. Chen, D. Y. Zhang, E. Gonzalez-Buendia, C. Lee-Chang, T. Xiao, G. Rothschild, , A. M. Sonabend

This study shows that CD8+ T-cells mediate immunoediting in murine gliomas, affecting genomic stability and immune evasion.

bioRxiv · Jul 16, 2019Cancer Biology