Author

C. Tkaczyk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

B. R. Sellman· 2 shared B. M. Peters· 1 shared E. Semenova· 1 shared J. E. Cassat· 1 shared K. R. Eichelberger· 1 shared K. Rosenthal· 1 shared K. Stover· 1 shared M. C. Noverr· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

B. R. Sellman

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Author profile →

2 papers

Recent·Most cited

A fungal metabolic regulator underlies infectious synergism during Candida albicans-Staphylococcus aureus intra-abdominal co-infection

S. Paul, O. A. Todd, K. R. Eichelberger, C. Tkaczyk, B. R. Sellman, M. C. Noverr, J. E. Cassat, P. L. Fidel, B. M. Peters

This study identifies ZCF13 in Candida albicans as a regulator of ribose metabolism that enhances synergistic virulence with Staphylococcus aureus during intra-abdominal infection.

bioRxiv · Feb 15, 2024 · PreprintMicrobiology

Alanine scanning mutagenesis of the Suvratoxumab epitope reduces alpha toxin lytic activity in vitro and S. aureus fitness in infection models

C. Tkaczyk, E. Semenova, Y. Shi, K. Rosenthal, V. Oganesyan, P. Warrener, K. Stover, B. R. Sellman

The paper mutates nine residues in the Suvratoxumab epitope of alpha toxin, showing reduced lytic activity and bacterial fitness, supporting the epitope's role in toxin function.

bioRxiv · May 16, 2018Microbiology