Author

C. Trappetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. C. Paton· 3 shared A. Calcutt· 1 shared A. Van Den Bergh· 1 shared B. A. Eijkelkamp· 1 shared E. B. Brazel· 1 shared F. G. Adams· 1 shared G. Martin· 1 shared H. Wang· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

J. C. Paton

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3 papers

Recent·Most cited

A phasevarion controls multiple virulence traits, including expression of vaccine candidates, in Streptococcus pneumoniae

Z. N. Phillips, C. Trappetti, A. Van Den Bergh, G. Martin, A. Calcutt, V. Ozberk, P. Guillon, M. Pandey, M. von Itzstein, W. E. Swords, J. C. Paton, M. P. Jennings, J. M. Atack

This study shows that the SpnIII phasevarion in S. pneumoniae affects multiple virulence traits and vaccine candidate expression, highlighting its importance in vaccine design.

bioRxiv · Feb 8, 2022 · PreprintMicrobiology

To make or take: bacterial lipid homeostasis during infection

F. G. Adams, C. Trappetti, J. K. Waters, M. Zang, E. B. Brazel, J. C. Paton, M. Snel, B. A. Eijkelkamp

This study investigates how Acinetobacter baumannii balances fatty acid synthesis and acquisition in different host niches during infection.

mBio · Jun 29, 2021Peer-reviewedMicrobiology

In Vivo Dual RNA-Seq Analysis Reveals the Basis for Differential Tissue Tropism of Clinical Isolates of Streptococcus pneumoniae

V. Minhas, R. Aprianto, L. J. McAllister, H. Wang, S. C. David, K. T. McLean, I. Comerford, S. R. McColl, J. C. Paton, J.-W. Veening, C. Trappetti

This study uses dual RNA-seq to show how a single SNP in Streptococcus pneumoniae affects bacterial and host gene expression, leading to differential tissue tropism and disease outcomes.

bioRxiv · Dec 3, 2019Microbiology